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Biolistic delivery to plant cells, also known as gene gun technology, was pioneered in the late 1980s. It involves propelling DNA-coated particles into plant tissues using a device like a gene gun. This technique revolutionized plant transformation, allowing direct DNA introduction into a wide range of plant species without the need for bacterial vectors.
Over the past 40 years, biolistic delivery technology has seen limited innovation. As materials scientists and engineers, we've pursued a fresh approach to this device since 2016 at Iowa State University. We've developed entirely new tools to augment the effectiveness of the current PDS-1000/He™ device manufactured by Bio-Rad. Additionally, we've created complementary lab supplies that enhance the efficiency of our new device, thereby reducing the consumption of resources in the laboratory.
Our research underscores the efficacy of the new device across various plant systems, showcasing its potential to bolster biolistic delivery efficiencies and streamline transgene-free editing in numerous crops. We anticipate that our technology will substantially rejuvenate and promote biolistic delivery method, fostering more effective gene delivery and editing while also minimizing the duration of tissue culture protocols across a diverse array of crops in the coming years.
Hermes Biomaterials Inc.
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